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Introduction to 3-MMC Crystals

buy 3mmc (3-Methylmethcathinone), also known as metaphedrone or 2-(methylamino)-1-(3-methylphenyl)propan-1-one, is a synthetic cathinone belonging to the substituted cathinone class of compounds . It is the ring-methylated positional isomer of 4-MMC (mephedrone), distinguished by the location of the methyl group on the phenyl ring . First formally notified as a new psychoactive substance by Sweden in September 2012, 3-MMC has since become one of the most prevalent synthetic cathinones monitored by the EU Early Warning System .

Following a decline in seizures between 2016 and 2019, 3-MMC re-emerged in Europe around 2020, with approximately 740 kilograms of powder seized that year alone—representing just over a quarter of the total quantity seized since monitoring began . As a research chemical, 3-MMC is primarily utilized as a certified reference material for forensic and toxicological applications, including GC-MS and LC-MS method development . At 4mmcchems, we supply premium-grade 3-MMC Crystals to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: 3-MMC Crystals (3-Methylmethcathinone)

Synonyms: Metaphedrone, 3-methyl MC, 2-(methylamino)-1-(3-methylphenyl)propan-1-one

CAS Number: 1246816-62-5 (hydrochloride salt)

Molecular Formula: C₁₁H₁₅NO · HCl

Molecular Weight: 213.70 g/mol (hydrochloride salt); 177.24 g/mol (free base)

Purity: ≥ 98% (verified by third-party HPLC/GC-MS testing)

Form: Crystalline solid; white to off-white crystalline powder

Storage: 2–8°C, dark, air-tight for maximum stability

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

3-MMC acts as a monoamine transporter modulator, functioning as both an inhibitor of reuptake and a substrate that induces neurotransmitter efflux . Unlike pure reuptake inhibitors, 3-MMC is transported into the presynaptic neuron and stimulates the release of dopamine, norepinephrine, and serotonin .

Key Pharmacological Data

Research has established the pharmacological profile of 3-MMC through in vitro assays:

• Transporter Activity: 3-MMC inhibits the reuptake of dopamine, norepinephrine, and serotonin while also inducing their release

• Potency Comparison: In comparison to 4-MMC, 3-MMC demonstrates greater potency at the dopamine transporter (DAT) and less potency at the serotonin transporter (SERT)

• DAT:SERT Ratio: The DAT:SERT ratio for 3-MMC is reported at approximately 9.6, compared to 2.4 for 4-MMC, indicating higher selectivity for dopamine systems

• EC₅₀ Values: For DAT-mediated release, 28 nM; for SERT-mediated release, 268 nM; for NET-mediated release, 27 nM

Research Applications

3-MMC is valuable for studying monoamine transporter dynamics, structure-activity relationships within the cathinone class, and comparative pharmacology of psychostimulants. It also serves as an analytical reference standard for identifying this compound in forensic samples, with certified reference materials available at concentrations of 1 mg/mL in methanol .

Why Choose 4mmcchems?

1. Uncompromising Quality

We source our 3-MMC Crystals from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and GC-MS testing to guarantee purity and potency. Reference standards are certified at ≥98.5% purity, with typical results exceeding 99.6% .

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

4mmcchems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: 3-MMC has been identified in 23 EU Member States, as well as Turkey and Norway . We have optimized shipping routes to ensure timely delivery across the continent, including Germany, France, the United Kingdom, Spain, Italy, the Netherlands, Switzerland, and more.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making 4mmcchems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Safety and Regulatory Information

3-MMC is a controlled substance in many jurisdictions globally. The World Health Organization’s Expert Committee on Drug Dependence has recommended that 3-MMC be added to Schedule II of the Convention on Psychotropic Substances of 1971 . The European Commission adopted measures to control 3-MMC across the EU following a risk assessment by the EMCDDA .

3-MMC is controlled in at least six EU Member States under new psychoactive substance legislation, including Austria, Belgium, Cyprus, Finland, Hungary, and Malta . It has been controlled in China since October 2015 .

Documented Health Risks

Clinical features of 3-MMC intoxication are consistent with other stimulants and include tachycardia, hypertension, agitation, aggression, hallucinations, rhabdomyolysis, and kidney failure . A total of 14 acute non-fatal poisonings with confirmed exposure to 3-MMC have been reported by four Member States .

Important Considerations for Researchers:

• Controlled Status: 3-MMC is a controlled substance in many countries and is under EU-wide control measures. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

• Research Use Only: This product is intended for research, forensic, and analytical applications only. Not for human or veterinary use .

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. Certified reference materials should be stored air-tight at 2–8°C in a dark location for maximum stability .

Shipping Information: Worldwide Delivery

4mmcchems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance, subject to local regulations.

How to Order

1. Browse Our Catalog: Select 3-MMC Crystals and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is 3-MMC used for in research?

A: 3-MMC is used as an analytical reference standard for forensic and toxicological applications, including GC-MS and LC-MS testing methods, transporter binding assays, and neuropharmacological studies .

Q: Is 3-MMC legal to purchase?

A: 3-MMC is a controlled substance in many countries and is subject to EU-wide control measures. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order .

Q: How should 3-MMC be stored?

A: Store air-tight at 2–8°C in a dark location for maximum stability. Certified reference solutions should be used shortly after opening to avoid concentration changes due to evaporation .

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries, especially given the controls on 3-MMC. Please refer to our shipping policy for more details.