Introduction to 4–Cl-PVP Crystals.

4-Cl-PVP, also known as 4-chloro-α-pyrrolidinovalerophenone, 4C-PVP, or 4-chloro-α-PVP, is a synthetic cathinone belonging to the pyrrolidinophenone class of compounds . It is the para-chlorinated analogue of the well-known stimulant α-PVP (alpha-pyrrolidinovalerophenone), distinguished by the substitution of a chlorine atom at the 4-position of the phenyl ring . While structurally similar to its parent compound, this halogenation significantly alters its chemical properties and potential interactions in research models .

As an emerging substance in forensic literature, 4-Cl-PVP has been identified in seizure samples and is primarily utilized as a certified reference material for forensic and analytical applications . At ForeverChems, we supply premium-grade 4-Cl-PVP Crystals to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: 4-Cl-PVP Crystals (4-Chloro-α-Pyrrolidinovalerophenone)

Synonyms: 4-chloro-α-PVP, 4C-PVP, 4′-chloro-α-pyrrolidinopentiophenone 

CAS Number: 5881-77-6 

Molecular Formula: C₁₅H₂₀ClNO 

Molecular Weight: 265.78 g/mol 

Purity: ≥ 98% (verified by third-party HPLC/GC-MS testing) 

Form: Crystalline solid 

Stereochemistry: Racemic mixture 

Storage: Store at -20°C for long-term stability 

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

4-Cl-PVP acts as a potent monoamine reuptake inhibitor, primarily targeting the dopamine and norepinephrine transporters . As a member of the pyrrolidinophenone class, it functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), preventing the reuptake of these neurotransmitters from the synaptic cleft and producing potent psychostimulant effects in research models .

Key Pharmacological Characteristics

• Mechanism: NDRI (Norepinephrine-Dopamine Reuptake Inhibitor) 

• Structural Class: Pyrrolidinophenone synthetic cathinone 

• Chiral Properties: Exists as a racemic mixture; the pyrrolidine ring creates a chiral centre at the C-2 carbon of the pentanone backbone 

• Related Compounds: Structurally similar to α-PVP (parent compound), MDPV, and other pyrovalerone-type cathinones 

Spectroscopic and Physical Properties

Research has characterized 4-Cl-PVP through various analytical methods. The crystalline solid exhibits:

• UV Absorption: Dominated by π-π* transitions

• Crystalline Form: The compound exists in salted forms; studies have confirmed the sulfate salt form in seizure samples 

• X-ray Crystallography: Provides valuable information on the enantiomeric forms and salt structures 

Emerging Research Status

As an emerging research chemical, detailed pharmacological and toxicological data for 4-Cl-PVP is still being established . It is presumed to share stimulant properties with other cathinones, but further research is required to fully characterize its effects and mechanisms . In forensic settings, it has been identified in drug seizures, often in combination with other substances .

Why Choose ForeverChems?

1. Uncompromising Quality

We source our 4-Cl-PVP Crystals from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and mass spectrometry testing to guarantee purity and potency, meeting the ≥98% purity threshold expected for analytical reference materials .

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

ForeverChems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: 4-Cl-PVP is controlled in multiple European jurisdictions. Germany has classified it under the NpSG (New Psychoactive Substances Act) for industrial and scientific use only . The United Kingdom lists it as a Class B substance . We have optimized shipping routes to ensure timely delivery to all EU member states, the UK, Switzerland, and more.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making ForeverChems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Regulatory and Safety Information

4-Cl-PVP is a regulated substance in many jurisdictions globally:

• United States: Schedule I Controlled Substance 

• Germany: NpSG (Industrial and scientific use only) 

• United Kingdom: Class B 

• Canada: Schedule I 

• Brazil: Class F2 (Prohibited psychotropics) 

Important Considerations for Researchers:

• Controlled Status: 4-Cl-PVP is a controlled substance in many countries. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

• Research Use Only: This product is intended for research, forensic, and analytical applications only . Not for human or veterinary use.

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. The crystalline solid should be stored at -20°C for long-term stability .

Shipping Information: Worldwide Delivery

ForeverChems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance, subject to local regulations.

How to Order

1. Browse Our Catalog: Select buy 4-Cl-PVP crystal and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is buy 4-Cl-PVP crystal used for in research?

A: buy 4-Cl-PVP is used as an analytical reference material for forensic and analytical applications, including GC-MS and LC-MS testing methods, structure elucidation studies, and pharmaceutical impurity analysis .

Q: Is buy 4-Cl-PVP crystal legal to purchase?

A: 4-Cl-PVP is a controlled substance in many countries, including the US, UK, Germany, and Canada . It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

Q: How should buy 4-Cl-PVP crystal be stored?

A: Store at -20°C for long-term stability. Protect from light and moisture .

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries, especially given the strict controls on buy 4-Cl-PVP crystal. Please refer to our shipping policy for more details.