Buy A-PHP Crystal | 4mmcchems – Premium Research Chemical.

 Introduction to A-PHP Crystal.

A PHP (alpha-Pyrrolidinohexanophenone), also known as PV-7, is a synthetic cathinone belonging to the pyrovalerone class of compounds. It is the higher homologue of alpha-PVP, distinguished by an additional carbon on the alkyl side chain . The compound was originally developed and patented in the 1960s but never marketed for therapeutic use .

As a research chemical, A-PHP is primarily utilized as a certified reference material for forensic and toxicological applications. Its detection in forensic casework across Europe has established it as an important standard for analytical method development. At 4mmcchems, we supply premium-grade A-PHP Crystal to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: A-PHP Crystal (alpha-Pyrrolidinohexanophenone)

Synonyms: PV-7, α-PHP

CAS Number: 13415-86-6

Molecular Formula: C₁₅H₂₃NO

Molecular Weight: 245.36 g/mol

Purity: ≥ 98% (verified by third-party HPLC/GC-MS testing)

Form: Crystalline solid

Storage: -20°C for long-term stability

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

A PHP acts as a potent inhibitor of the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). Research demonstrates that A-PHP functions as a pure uptake inhibitor, meaning it blocks the reuptake of neurotransmitters without inducing their release . This mechanism distinguishes it from some other cathinones that act as substrate releasers.

Key Pharmacological Data

• DAT Inhibition: A-PHP is a potent dopamine transporter inhibitor, with effects comparable to strong stimulants such as methamphetamine and MDPV .

• Rank Order of Potency: DAT > NET >> SERT, indicating high selectivity for the dopamine system .

• Serum Half-Life: Pharmacokinetic analyses suggest a serum elimination half-life of approximately 37 hours, contributing to its long-lasting effects .

• Metabolism: More than 20 metabolites have been reported, with pyrrolidine ring oxidation being the predominant pathway in humans .

Research Applications

A-PHP is valuable for studying dopamine transporter dynamics, structure-activity relationships within the cathinone class, and comparative pharmacology of psychostimulants.

Why Choose 4mmcchems?

1. Uncompromising Quality

We source our A PHP Crystal from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and GC-MS testing to guarantee purity and potency, meeting the ≥98% purity threshold required for analytical reference materials.

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

4mmcchems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: A PHP has been detected in 21 EU Member States and is controlled in at least seven . We have optimized shipping routes to ensure timely delivery to all EU member states, the UK, Switzerland, and more.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making 4mmcchems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Safety and Regulatory Information

A-PHP is a controlled substance in many jurisdictions globally. The World Health Organization has recommended that A PHP be added to Schedule II of the Convention on Psychotropic Substances of 1971 . The compound has been associated with at least 27 deaths and two acute poisonings across Europe .

Important Considerations for Researchers:

• Controlled Status: A-PHP is a Schedule I Controlled Substance in the United States, a Class B substance in the UK, and is controlled in Italy, Sweden, and China . It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

• Research Use Only: This product is intended for research, forensic, and analytical applications only. Not for human or veterinary use .

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. A-PHP is associated with serious adverse effects including agitation, paranoia, hypertension, tachycardia, and seizures .

Shipping Information: Worldwide Delivery

4mmcchems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance, subject to local regulations.

How to Order

1. Browse Our Catalog: Select A-PHP Crystal and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is A-PHP used for in research?

A: A-PHP is used as an analytical reference material for forensic and toxicological applications, including GC-MS and LC-MS testing methods, transporter binding assays, and neuropharmacological studies .

Q: Is A-PHP legal to purchase?

A: A PHP is a controlled substance in many countries, including the US, UK, Italy, Sweden, and China . It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

Q: How should A PHP be stored?

A: Store at -20°C for long-term stability. Protect from light and moisture.

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries, especially given the strict controls on A PHP. Please refer to our shipping policy for more details.